PTPRB Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PTPRB |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: PTPRB antibody detects endogenous levels of total PTPRB. Function: Plays an important role in blood vessel remodeling and angiogenesis. Not necessary for the initial formation of blood vessels, but is essential for their maintenance and remodeling. Can induce dephosphorylation of TEK/TIE2, CDH5/VE-cadherin and KDR/VEGFR-2. Regulates angiopoietin-TIE2 signaling in endothelial cells. Acts as a negative regulator of TIE2, and controls TIE2 driven endothelial cell proliferation, which in turn affects blood vessel remodeling during embryonic development and determines blood vessel size during perinatal growth. Essential for the maintenance of endothelial cell contact integrity and for the adhesive function of VE-cadherin in endothel |
| Immunogen | Immunogen: A synthesized peptide derived from human PTPRB Subcellular Location: Membrane. Tissue Specificity: Up-regulated by hypoxia. Predicted Cross Reactivity: Pig, Rabbit Similarity: Pig (82%), Rabbit (82%) |
| Other Names | [receptor-type tyrosine-protein phosphatase beta isoform a; Receptor-type tyrosine-protein phosphatase beta; receptor-type tyrosine-protein phosphatase beta; protein tyrosine phosphatase, receptor type B; Vascular endothelial protein tyrosine phosphatase; VE-PTP] |
| Gene, Accession # | [PTPRB], Gene ID: 5787, NCBI: NP_001103224.1, UniProt: P23467 |
| Catalog # | MBS9610157 |
| Price | $240, $280 |
| Order / More Info | PTPRB Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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