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Antigenic Specificity | Phospho-STAM2 (Tyr371) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mousepredicted: porcine, bovine, horse, sheep, rabbit, dog, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Peptide ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-STAM2 (Tyr371) Antibody detects endogenous levels of STAM2 only when phosphorylated at Tyr371. Description: Involved in intracellular signal transduction mediated by cytokines and growth factors. Upon IL-2 and GM-CSL stimulation, it plays a role in signaling leading to DNA synthesis and MYC induction. May also play a role in T-cell development. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with HGS (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes (By similarity).Post Translational Modifications: Phospho |
Immunogen | Immunogen: A synthesized peptide derived from human STAM2 around the phosphorylation site of Tyr371. Tissue Specificity: Ubiquitously expressed. |
Other Names | [DKFZp564C047; Hbp; Hrs-binding protein; HSE1 homolog; Signal transducing adapter molecule 2; Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2; Signal transducing adaptor molecule 2A; Signal transducing adaptor molecule 2B; Signal transducing adaptor molecule; STAM like protein containing SH3 and ITAM domains 2; STAM-2; Stam2; STAM2_HUMAN; STAM2A; STAM2B] |
Gene, Accession # | [STAM2], Gene ID: 10254, NCBI: NP_005834.4, UniProt: O75886 |
Catalog # | MBS9610520 |
Price | $225, $280, $340 |
Order / More Info | Phospho-STAM2 (Tyr371) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |