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Antigenic Specificity | Caspase 3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | epitope affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | 1.0 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous level of total Caspase 3 protein. Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. |
Immunogen | Immunogen Type: Peptide-KLH Immunogen Description: Peptide sequence around aa.29~33 (S-G-I-S-L) derived from Caspase 3. |
Other Names | [Apopain] |
Gene, Accession # | Gene ID: 836, NCBI: NP_004337.2, UniProt: P42574 |
Catalog # | MBS9403676 |
Price | $200, $255 |
Order / More Info | Caspase 3 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |