Bmi-1, aa1-202 (RNF51, MGC12685, BUP, Polycomb Group RING Finger Protein 4) Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-Bmi-1, aa1-202 (RNF51, MGC12685, BUP, Polycomb Group RING Finger Protein 4) antibody, protein, ELISA kits.
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| Antigenic Specificity | Bmi-1, aa1-202 (RNF51, MGC12685, BUP, Polycomb Group RING Finger Protein 4) |
| Clone | [1.T.21] |
| Host Species | Mouse |
| Reactive Species | human, mouse, rabbit, rat |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.05 mg, 0.1 mg |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC). Other applications have not been tested. |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recognizes mouse Bmi-1 (triplet), Mr 40-44kD.Species Crossreactivity: human, rat and rabbit. Bmi1 is a member of the polycomb group (PcG) proteins. PcG proteins form multiprotein complexes that function as transcriptional repressors. Several lines of evidence implicate Bmi1 in tumorigenesis. Firstly, Bmi1 cooperates with c-Myc in the generation of lymphomas in double transgenic mice. Secondly, Bmi1 blocks senescence and immortalizes mouse embryo fibroblasts, although not human fibroblasts, and in combination with an activated H-ras gene leads to neoplastic transformation. Thirdly, the BMI1 gene is amplified in certain mantle cell lymphomas and is overexpressed in a subset of non-small cell lung cancer, colorectal carcinomas, multiple myelom |
| Immunogen | Immunogen: Recombinant Bmi-1 protein corresponding to aa1-202 of mouse Bmi-1 (NP_005171). |
| Other Names | [-Bmi-1, aa1-202 (RNF51, MGC12685, BUP, Polycomb Group RING Finger Protein 4)], [bmi1; bmi-1; pcgf4; rnf51; xbmi-1] |
| Gene, Accession # | Gene ID: 548749, NCBI: NP_001015995.1 |
| Catalog # | MBS602584 |
| Price | $520, $875 |
| Order / More Info | Bmi-1, aa1-202 (RNF51, MGC12685, BUP, Polycomb Group RING Finger Protein 4) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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