PRKRA Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | PRKRA |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | fluorescein (FITC) conjugate |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Activates EIF2AK2/PKR in the absence of double-stranded RNA (dsRNA), leading to phosphorylation of EIF2S1/EFI2-alpha and inhibition of translation and induction of apoptosis. Required for siRNA production by DICER1 and for subsequent siRNA-mediated post-transcriptional gene silencing. Does not seem to be required for processing of pre-miRNA to miRNA by DICER1. Promotes UBC9-p53/TP53 association and sumoylation and phosphorylation of p53/TP53 at 'Lys-386' at 'Ser-392' respectively and enhances its activity in a EIF2AK2/PKR-dependent manner (By similarity). |
| Immunogen | Immunogen: Recombinant human Interferon-inducible double-stranded RNA-dependent protein kinase activator A protein Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-18768 / sc-32010 / sc-292629 |
| Other Names | [Interferon-inducible double-stranded RNA-dependent protein kinase activator A; PRKRA; PACT; RAX; HSD-14; HSD14; PKR-associated protein X; PKR-associating protein X; Protein activator of the interferon-induced protein kinase; Protein kinase; interferon-inducible double-stranded RNA-dependent activator], [PRKRA; PRKRA; RAX; PACT; DYT16; HSD14; PACT; RAX] |
| Gene, Accession # | [PRKRA], Gene ID: 8575, NCBI: NP_001132989.1, UniProt: O75569 |
| Catalog # | MBS1493343 |
| Price | $160, $235 |
| Order / More Info | PRKRA Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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