PIASy1 (C-term), 471-499 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PIASy1 (C-term), 471-499 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PIASy1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 471-499 amino acids from the C-terminal region of human PIASy1. PIASy1 functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. This protein plays a crucial role in transcriptional coregulation of various cellular pathways, including the STAT pathway, the p53 pathway, the wnt pathway and the steroid hormone signaling pathway. PIASy1 is involved in gene silencing, and promotes PARK7 sumoylation. |
| Immunogen | n/a |
| Other Names | [E3 SUMO-protein ligase PIAS4; 632-; PIASy; Protein inhibitor of activated STAT protein 4; Protein inhibitor of activated STAT protein gamma; PIAS-gamma; PIAS4; PIASG] |
| Gene, Accession # | [PIAS4], Gene ID: 51588, NCBI: NP_056981.2, UniProt: Q8N2W9 |
| Catalog # | MBS9214238 |
| Price | $165, $370 |
| Order / More Info | PIASy1 (C-term), 471-499 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Imoto, S., et al., J. Biol. Chem. 278(36):34253-34258 (2003). Chun, T.H., et al., Circ. Res. 92(11):1201-1208 (2003). Subramanian, L., et al., J. Biol. Chem. 278(11):9134-9141 (2003). Liu, B., et al., Proc. Natl. Acad. Sci. U.S.A. 98(6):3203-3207 (2001). Liu, B., et al., Proc. Natl. Acad. Sci. U.S.A. 95(18):10626-10631 (1998). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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