TNF-RII, Human Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | TNF-RII, Human |
| Clone | MR2-1 |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | IgG1 |
| Format | Protein G purified |
| Size | 0.5 mg |
| Concentration | 1.70 mg/mL |
| Applications | Immunohistochemistry (IHC) Formalin,Flow Cytometry (FC/FACS),Functional Studies (FS), Immuno Assays (IA), Immunofluorescence (IF), Immunoprecipitation (IP),Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | The antibody MR2-1 reacts with the extra-cellular part of the TNF-RII. It also reacts with the soluble receptor. TNF-RII is present on most cell types and is considered to play a prominent role in cell stimulation by TNF-alpha. TNF-RII molecule is shown to be responsible for stimulation of activated T-lymphocytes by TNF-alpha. The antibody cross reacts with rhesus and cynomolgus natural TNF-RII. |
| Immunogen | Immunogen: sTNF -R75 purified from the culture supernatant of NSO cells (transfected with the extracellular part of TNF - R75) (Ref.1). Aliases: Tumor necrosis factor receptor superfamily member 1B, Tumor necrosis factor receptor 2, TNF-R2, Tumor necrosis factor receptor type II, TNFR-II, p75, p80 TNF-alpha receptor, CD120b |
| Other Names | [tumor necrosis factor receptor superfamily member 1B; Tumor necrosis factor receptor superfamily member 1B; tumor necrosis factor receptor superfamily member 1B; TNF receptor superfamily member 1B; Tumor necrosis factor receptor 2; TNF-R2], [TNFRSF1B; TNFRSF1B; p75; TBPII; TNFBR; TNFR2; CD120b; TNFR1B; TNFR80; TNF-R75; p75TNFR; TNF-R-II; TNFBR; TNFR2; TNF-R2; TNF-RII; TNFR-II] |
| Gene, Accession # | [TNF-RII], Gene ID: 7133, NCBI: NP_001057.1, UniProt: P20333 |
| Catalog # | MBS584726 |
| Price | $1665 |
| Order / More Info | TNF-RII, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Leeuwenberg, JFM et al; Slow release of soluble TNF-Receptors by monocytes in vitro. J Immunol 1994, 152: 4036 2. Leeuwenberg, JFM et al; Lipopolysaccharide LPS-mediated soluble TNF-Receptor release and TNF-Receptor expression by monocytes; role of CD14, LPS binding protein and bactericidal/permeability-increasing protein. J Immnol 1994, 152: 5070 3. Marchetti, L et al; Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa B pathway. J Biol Chem 2004, 279: 32869 |
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MYBIOSOURCE INC.
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