Human Mitogen-activated protein kinase 7 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Mitogen-activated protein kinase 7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size0.05 mL, 0.1 mL
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionPlays a role in various cellular processes such as proliferation, differentiation and cell survival. The upstream activator of MAPK7 is the MAPK kinase MAP2K5. Upon activation, it translocates to the nucleus and phosphorylates various downstream targets including MEF2C. EGF activates MAPK7 through a Ras-independent and MAP2K5-dependent pathway. May have a role in muscle cell differentiation. May be important for endothelial function and maintenance of blood vessel integrity. MAP2K5 and MAPK7 interact specifically with one another and not with MEK1/ERK1 or MEK2/ERK2 pathways. Phosphorylates SGK1 at Ser-78 and this is required for growth factor-induced cell cycle progression. Involved in the regulation of p53/TP53 by disrupting the PML-MDM2 i
ImmunogenImmunogen: Recombinant human Mitogen-activated protein kinase 7 protein(1-310aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1286 / sc-1284 / sc-1285 / sc-5626
Other Names[MAP kinase 7; MAPK 7; Big MAP kinase 1; BMK-1; Extracellular signal-regulated kinase 5; ERK-5; MAPK7; BMK1; ERK5; PRKM7], [MAPK7; MAPK7; BMK1; ERK4; ERK5; PRKM7; BMK1; ERK5; PRKM7; MAP kinase 7; MAPK 7; BMK-1; ERK-5]
Gene, Accession #[MAPK7], Gene ID: 5598, NCBI: NP_002740.2, UniProt: Q13164
Catalog #MBS1493920
Price$120, $160
Order / More InfoHuman Mitogen-activated protein kinase 7 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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