PUMA / bbc3 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPUMA / bbc3
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentration0.5 mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionBackground: PUMA (p53 upregulated modulator of apoptosis) is one of the pro-apoptotic Bcl-2 family members which are also transcriptional targets of p53. PUMA gene encodes two BH3 domain-containing proteins termed PUMA-alpha and PUMA-beta. PUMA proteins bind Bcl-2, localize to the mitochondria, and induce cytochrome c release and apoptosis in response to p53. PUMA may be a direct mediator of p53-induced apoptosis.
ImmunogenImmunogen: Synthetic peptide surrounding amino acid 177 of human PUMA. Positive Control: Western Blot: Jurkat cells and Rat kidney tissue, IHC: Tonsil tissue
Other Names[PUMA/JFY1,JFY-1; PUMA; BBC3; bcl-2 binding component 3], [BBC3; BBC3; JFY1; PUMA; JFY-1; PUMA]
Gene, Accession #[PUMA/bbc3], Gene ID: 27113, NCBI: NP_001120712.1, UniProt: Q9BXH1
Catalog #MBS840219
Price$150, $290
Order / More InfoPUMA / bbc3 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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