IKBKE Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | IKBKE |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | affinity purified |
| Size | 0.05 mL, 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: IKBKE antibody detects endogenous levels of total IKBKE. Description: Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon.The transcription factor NFkappaB is retained in the cytoplasm in an inactive form by the inhibitory protein IkappaB. Activation of NFkappaB requires that IkappaB be phosphorylated on specific serine residues, which results in targeted degra-dation of IkappaB. IkappaB kinase alpha(IKKalpha), previously designated CHUK, interacts with IkappaB-alphaand specifically phosphorylates IkappaB-alphaon the sites that trigger its degradation, serines 32 and 36. The functional IKK complex contains three subunits, IKKalpha, IKKbetaand IKKgamma(also designated NEMO), and each appear to make esse |
| Immunogen | Immunogen: Purified recombinant fragment of human IKBKE expressed in E. Coli Subcellular Location: Cytoplasm. Nucleus. Nucleus > PML Body. Targeting to PML nuclear bodies upon DNA damage is TOPORS-dependent. Tissue Specificity: Highly expressed in spleen followed by thymus, peripheral blood leukocytes, pancreas, placenta. Weakly expressed in lung, kidney, prostate, ovary and colon. |
| Other Names | [I kappa B kinase epsilon; I-kappa-B kinase epsilon; IkBKE; IKK related kinase epsilon; IKK-E; IKK-epsilon; IKK-i; IKKE; IKKE_HUMAN; IKKepsilon; IKKI; Inducible I kappa B kinase; Inducible I kappa-B kinase; Inducible IkappaB kinase; Inhibitor of kappa light polypeptide gene enhancer in B cells kinase epsilon; Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase of, epsilon; Inhibitor of nuclear factor kappa-B kinase subunit epsilon; KIAA0151; MGC125294; MGC125295; MGC125297] |
| Gene, Accession # | [IKBKE], Gene ID: 9641, NCBI: NP_001180250.1, UniProt: Q14164 |
| Catalog # | MBS9602715 |
| Price | $235, $295, $370 |
| Order / More Info | IKBKE Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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