BAG2 (C-term), 148-176 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | BAG2 (C-term), 148-176 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human (predicted reactivity: bovine, mouse) |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This BAG2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-176 amino acids from the C-terminal region of human BAG2. BAG proteins compete with Hip for binding to theHsc70/Hsp70 ATPase domain and promote substrate release. All theBAG proteins have an approximately 45-amino acid BAG domain nearthe C terminus but differ markedly in their N-terminal regions. Thepredicted BAG2 protein contains 211 amino acids. The BAG domains ofBAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPasedomain in vitro and in mammalian cells. All 3 proteins bind withhigh affinity to the ATPase domain of Hsc70 and inhibit itschaperone activity in a Hip-repressible manner. [provide |
| Immunogen | n/a |
| Other Names | [BAG family molecular chaperone regulator 2; BAG-2; Bcl-2-associated athanogene 2; BAG2] |
| Gene, Accession # | [BAG2], Gene ID: 9532, NCBI: NP_004273.1, UniProt: O95816 |
| Catalog # | MBS9211945 |
| Price | $165, $370 |
| Order / More Info | BAG2 (C-term), 148-176 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Arndt, V., et al. Mol. Biol. Cell 16(12):5891-5900(2005) Dai, Q., et al. J. Biol. Chem. 280(46):38673-38681(2005) Ueda, K., et al. J. Biol. Chem. 279(40):41815-41821(2004) Ueda, K., et al. J. Biol. Chem. 279(40):41815-41821(2004) Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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