Mouse CD11b Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMouse CD11b
Clone[mCD11b]
Host SpeciesRat
Reactive Speciesn/a
IsotypeIgG2b
Formatfluorescein (FITC) conjugate
Size0.5 mg, 1 mg
Concentration1mg/ml in PBS (after reconstitution).
Applicationsn/a
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DescriptionIntroduction: Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Integrin alpha-m/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. CD-11b is identical with cr-3, the receptor for the ic3b fragment of
ImmunogenImmunogen: Purified mouse LN CD4 T cells. Antibody Properties: Staining and blocking antibody. For staining, use 10 ul/1,000,000 cells. This antibody will block signaling through the CD11a molecule. Titer for blocking should be determined by the investigator. Available Conjugates: This antibody is only available conjugated to FITC.
Other Names[CD11b FITC; CD11b FITC, Rat Mouse; Integrin; alpha M; CR3A; MO1A; CD11B; MAC-1; MAC1A; MGC117044; ITGAM TypeRat Mouse; CD11b FITC], [ITGAM; CD11b; CD11B]
Gene, Accession #[CD11b], Gene ID: 397459, NCBI: AAB16869.1
Catalog #MBS140037
Price$305, $455
Order / More InfoMouse CD11b Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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