LMP2 Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-LMP2 antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | LMP2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | Epstein-Barr virus |
| Isotype | n/a |
| Format | Protein G purified |
| Size | 0.05 mg, 0.1 mg |
| Concentration | n/a |
| Applications | ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Isoform LMP2A maintains EBV latent infection of B-lymphocyte, by preventing lytic reactivation of the virus in response to surface immunoglobulin (sIg) cross-linking. Acts like a dominant negative inhibitor of the sIg-associated protein tyrosine kinases, LYN and SYK. Also blocks translocation of the B-cell antigen receptor (BCR) into lipid rafts, preventing the subsequent signaling and accelerated internalization of the BCR upon BCR cross-linking. Serves as a molecular scaffold to recruit SYK, LYN and E3 protein-ubiquitin ligases, such as ITCH and NEDD4L, leading to ubiquitination and potential degradation of both tyrosines kinases. Possesses a constitutive signaling activity in non-transformed cells, inducing bypass of normal B lymphocyte |
| Immunogen | Immunogen: Recombinant Epstein-Barr virus Latent membrane protein 2 protein (1-147AA) Conjugation: Non-conjugated |
| Other Names | [Latent membrane protein 2; Terminal protein; LMP2] |
| Gene, Accession # | [LMP2], Gene ID: 17494212, NCBI: YP_401631.1, UniProt: P13285 |
| Catalog # | MBS7052617 |
| Price | $160, $235 |
| Order / More Info | LMP2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies