Edit |   |
Antigenic Specificity | Phospho-ATF2 (S322) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ATF2 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S322 of human ATF2. ATF2 is a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. |
Immunogen | n/a |
Other Names | [Cyclic AMP-dependent transcription factor ATF-2; cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding protein 2; HB16; Histone acetyltransferase ATF2; cAMP response element-binding protein CRE-BP1; ATF2; CREB2; CREBP1] |
Gene, Accession # | [ATF2], Gene ID: 1386, NCBI: NP_001243019.1, UniProt: P15336 |
Catalog # | MBS9201187 |
Price | $165, $370 |
Order / More Info | Phospho-ATF2 (S322) Antibody from MYBIOSOURCE INC. |
Product Specific References | Kravets, A., et al., J. Biol. Chem. 279(19):19916-19923 (2004). Hong, S., et al., J. Biol. Chem. 279(17):16996-17003 (2004). Averous, J., et al., J. Biol. Chem. 279(7):5288-5297 (2004). Berger, A.J., et al., Cancer Res. 63(23):8103-8107 (2003). Wen-Sheng, W., Oncogene 22(7):955-963 (2003). |