IL-1ra3, Human Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | IL-1ra3, Human |
| Clone | 2D11 |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | F, Immunoasssay (IA), Western Blot |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The antibody reacts specificly with Human IL-1ra3. IL-1ra3 belongs to the IL-1 system which includes two agonists (IL-1alpha and IL-1beta), converting enzymes, antagonists, two receptors (IL-1 R I and IL-1 R II) and the IL-1 receptor accessory protein. Three molecular isoforms of the IL-1 receptor antagonist (IL-1ra) have been identified and cloned. Secreted IL-1ra (sIL-1ra or IL-1ra1) contains a classical leader peptide giving a released mature protein. Two intracellular isoforms, icIL-1ra type I (IL-1ra2) and icIL-1 ra type II (IL-1ra3), have no leader sequence, thus predicting that these proteins remain intracellular. IL-1ra3 may represent a reservoir of IL-1 inhibitors, released upon cell death, whose function is to |
| Immunogen | n/a |
| Other Names | [interleukin-1 receptor antagonist protein isoform 4; Interleukin-1 receptor antagonist protein; interleukin-1 receptor antagonist protein; IL1 inhibitor; IL1RN (IL1F3); type II interleukin-1 receptor antagonist; intracellular IL-1 receptor antagonist type II; intracellular interleukin-1 receptor antagonist (icIL-1ra); interleukin 1 receptor antagonist; ICIL-1RA; IL1 inhibitor; INN: Anakinra], [IL1RN; IL1RN; DIRA; IRAP; IL1F3; IL1RA; MVCD4; IL-1RN; IL-1ra; IL-1ra3; ICIL-1RA; IL1F3; IL1RA; IL-1RN; IL-1ra; IRAP] |
| Gene, Accession # | [IL-1ra3], Gene ID: 3557, NCBI: NP_776215.1 |
| Catalog # | MBS584311 |
| Price | $520 |
| Order / More Info | IL-1ra3, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Muzio, M et al; Cloning and characterization of a new isoform of the Interleukin 1 receptor antagonist. J Exp Med 1995, 182: 623 2. Muzio, M et al; Characterization of type II intracellular IL-1 receptor antagonist (IL-1ra3): a depot IL-1ra. Eur J Immunol 1999, 29: 781 |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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