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Antigenic Specificity | RAF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 1 mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RAF1 is the cellular homolog of viral raf gene (v-raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine/threonine specific protein kinases, ERK1 and ERK2. |
Immunogen | Immunogen: RAF1 antibody was raised in Rabbit using the peptide sequence around phosphorylation site of serine 338 (R-D-S(p)-S-Y) derived from Human RAF as the immunogen. |
Other Names | [Rabbit RAF1; RAF1; RAF1; RAF 1; Phospho Ser338; CRAF; RAF 1; Phospho Ser259; RAF-1; RAF1; RAF-1] |
Gene, Accession # | [RAF1], Gene ID: 5894, NCBI: AAA60247.1 |
Catalog # | MBS5309573 |
Price | $295 |
Order / More Info | RAF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |