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Antigenic Specificity | Beta-actin |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mg |
Concentration | 1 mg/ml |
Applications | ELISA, Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Actins are highly conserved proteins that are involved in cell motility, structure and integrity, processes that are crucial for tissue development and the development of organism. The actin cytoskeleton is one of the principal drivers of cell motility and is capable of responding to complex signaling cascades. Recent evidence suggests that it may play key roles in regulating apoptosis and aging. Beta actin is one of six different actin isoforms which have been identified. Like GAPDH, beta-actin is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots. |
Immunogen | Immunogen: 16 amino acid peptide from near the amino-terminus of human b-actin. |
Other Names | [Beta actin; b actin; (NT) a major cytoskeletal protein; N Terminus], [ACTB; ACTB; BRWS1; PS1TP5BP1] |
Gene, Accession # | Gene ID: 60, NCBI: AAH02409, UniProt: P60709 |
Catalog # | MBS150383 |
Price | $375 |
Order / More Info | Beta-actin Antibody from MYBIOSOURCE INC. |
Product Specific References | * Lambrechts A, Van Troys, M and Ampe C. The actin cytoskeleton in normal and pathological cell motility. Int. J. Biochem. Cell Biol. 2004; 36:1890-909.* Gourlay CW and Ayscough KR. The actin cytoskeleton: a key regulator of apoptosis and ageing. Nat. Rev. 2005; 6:583-9. |