gp100/Melanosome/PMEL17/SILV (Melanoma Marker) Antibody from MYBIOSOURCE INC.

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Antigenic Specificitygp100/Melanosome/PMEL17/SILV (Melanoma Marker)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Paraffin
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DescriptionSpecificity: Cytotoxic T lymphocytes (CTL's) recognize melanoma-associated antigens, which belong to three main groups. These groups include tumor-associated testis-specific antigens, melanocyte differentiation antigens and mutated or aberrantly expressed antigens, which are routinely used as markers to identify melanomas based on their binding to specific monoclonal antibodies. gp100, also designated ME20-M, ME20-S and PMEL 17, is classified as a melanocyte differentiation antigen and is expressed at low levels in normal cell lines and tissues, but is upregulated in melanocytes. gp100 is a highly glycosylated protein. It is also the product of proteolytic cleavage, which results in a secreted protein.
ImmunogenImmunogen: Recombinant full-length human SILV protein
Other Names[95kDa melanocyte-specific secreted glycoprotein; M-beta; Melanocyte lineage specific antigen GP100; Melanocyte protein Pmel 17; Melanoma associated ME20 antigen; Melanosomal matrix protein17; p100; p26; PMEL17; Premelanosome protein; Secreted melanoma-associated ME20 antigen; SILV; Silver homolog]
Gene, Accession #[SILV], Gene ID: 6490, NCBI: P40967.2, UniProt: P40967
Catalog #MBS4381251
Price$190, $340, $340
Order / More Infogp100/Melanosome/PMEL17/SILV (Melanoma Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesAdema, G.J., et al. 1994. Molecular characterization of the melanocyte lineage-specific antigen gp100. J. Biol. Chem. 269: 20126-20133.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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