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Antigenic Specificity | TRIB1 (C-term), 341-370 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: mouse) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This TRIB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the C-terminal region of human TRIB1. TRIB1 antibody, also called gprotein coupled receptor induced, skip1, gig2, c8fwATP, functions in binding protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities.Overexpression of TRIB1 in HeLa cells repressed the basal activity of the IL8 promoter by inhibiting AP1 activity. Overexpression of TRIB1 inhibited oncogenic Ras -driven AP1 activation and MEKK1-mediated AP1 activation. ERK activation was enhanced by TRIB1. Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3, and MKK4 int |
Immunogen | n/a |
Other Names | [Tribbles homolog 1; TRB-1; G-protein-coupled receptor-induced gene 2 protein; GIG-2; SKIP1; TRIB1 HGNC:16891)] |
Gene, Accession # | [TRIB1], Gene ID: 10221, NCBI: NP_079471.1, UniProt: Q96RU8 |
Catalog # | MBS9208076 |
Price | $165, $370 |
Order / More Info | TRIB1 (C-term), 341-370 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kiss-Toth, E., et al., J. Biol. Chem. 279(41):42703-42708 (2004). Wu, M., et al., J. Biol. Chem. 278(29):27072-27079 (2003). Wilkin, F., et al., Eur. J. Biochem. 248(3):660-668 (1997). |