TRIB1 (C-term), 341-370 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityTRIB1 (C-term), 341-370
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: mouse)
Isotypen/a
Formatpurified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 2
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis TRIB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the C-terminal region of human TRIB1. TRIB1 antibody, also called gprotein coupled receptor induced, skip1, gig2, c8fwATP, functions in binding protein binding, protein kinase inhibitor activity, and protein serine/threonine kinase activities.Overexpression of TRIB1 in HeLa cells repressed the basal activity of the IL8 promoter by inhibiting AP1 activity. Overexpression of TRIB1 inhibited oncogenic Ras -driven AP1 activation and MEKK1-mediated AP1 activation. ERK activation was enhanced by TRIB1. Coimmunoprecipitation and yeast 2-hybrid assays showed that MEK1 interacted with both TRIB1 and TRIB3, and MKK4 int
Immunogenn/a
Other Names[Tribbles homolog 1; TRB-1; G-protein-coupled receptor-induced gene 2 protein; GIG-2; SKIP1; TRIB1 HGNC:16891)]
Gene, Accession #[TRIB1], Gene ID: 10221, NCBI: NP_079471.1, UniProt: Q96RU8
Catalog #MBS9208076
Price$165, $370
Order / More InfoTRIB1 (C-term), 341-370 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKiss-Toth, E., et al., J. Biol. Chem. 279(41):42703-42708 (2004). Wu, M., et al., J. Biol. Chem. 278(29):27072-27079 (2003). Wilkin, F., et al., Eur. J. Biochem. 248(3):660-668 (1997).
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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