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Antigenic Specificity | Human Programmed Cell Death 1 |
Clone | [P4F12AT] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG2b k |
Format | Protein G purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Introduction: PDCD1 is a cell surface membrane protein of the immunoglobulin superfamily. PDCD1 is expressed in pro-B-cells and is thought to have a role in their differentiation. In mice, expression of PDCD1 gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for the PDCD1 gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that the PDCD1 gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. |
Immunogen | Immunogen: Anti-human PDCD1 mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PDCD1 amino acids 21-167 purified from E Coli. |
Other Names | [PDCD1; Programmed cell death protein 1, Mouse Human; Programmed cell death protein 1; Protein PD-1; hPD-1; CD279; PDCD1; PD1; SLEB2], [PDCD1; PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; PD1; Protein PD-1; hPD-1] |
Gene, Accession # | [PDCD1], Gene ID: 5133, NCBI: NP_005009.2 |
Catalog # | MBS140297 |
Price | $140, $205, $505 |
Order / More Info | Human Programmed Cell Death 1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |