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Antigenic Specificity | C3/C3b |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.1 mL |
Concentration | 0.9mg/ml |
Applications | Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of total C3/C3b protein. Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. The encoded preproprotein is proteolytically processed to generate alpha and beta subunits that form the mature protein, which is then further processed to generate numerous peptide products. The C3a peptide, also known as the C3a anaphylatoxin, modulates inflammation and possesses antimicrobial activity. Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients. |
Immunogen | Immunogen: Synthetic peptide corresponding to internal residues of human C3, C3b Immunogen Type: Peptide |
Other Names | [ASP; C3a; C3b; AHUS5; ARMD9; CPAMD1; HEL-S-62p] |
Gene, Accession # | [C3/C3b], Gene ID: 718, NCBI: NP_000055, UniProt: P01024 |
Catalog # | MBS9429520 |
Price | $255 |
Order / More Info | C3/C3b Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |