PAK2 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | PAK2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit polyclonal to Human PAK2. The p21-activated kinase (PAK) family of serine/threonine kinases is engaged in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, control of phagocyte NADPH oxidase, and growth factor-induced neurite outgrowth (1,2). Several mechanisms that induce PAK activity have been reported. Binding of Rac/Cdc42 to the CRIB (or PBD) domain near the amino terminus of PAK causes autophosphorylation and conformational changes in PAK (1). Phosphorylation of PAK1 at Thr423 by PDK induces activation of PAK1 (3). Several autophosphorylation sites have been identified, including Ser199 and Ser204 of PAK1 and Ser192 and Ser197 of PAK2 (4,5). Because the autophosphorylation s |
| Immunogen | Immunogen: A Fusion protein of human PAK2 |
| Other Names | [PAK2; PAK2; PAK65; PAKgamma], [PAK2; PAK2; PAK65; PAKgamma; PAK-2; p27; p34] |
| Gene, Accession # | Gene ID: 5062, NCBI: NP_002568.2, UniProt: Q13177 |
| Catalog # | MBS125768 |
| Price | $275, $430 |
| Order / More Info | PAK2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Knaus, U.G. and Bokoch, G.M. (1998) Int. J. Biochem. Cell Biol. 30, 857-862. 2. Daniels, R.H. et al. (1998) EMBO J. 17, 754-764. 3. King, C.C. et al. (2000) J. Biol. Chem. 275, 41201-41209. 4. Manser, E. et al. (1997) Mol. Cell. Biol. 17, 1129-1143. 5. Gatti, A. et al. (1999) J. Biol. Chem. 274, 8022-8028. 6. Lei, M. et al. (2000) Cell 102, 387-397. 7. Chong, C. et al. (2001) J. Biol. Chem. 276, 17347-17353. 8. Zhao, Z. et al. (2000) Mol. Cell. Biol. 20, 3906-3917. 9. Abo, A. et al. (1998) EMBO J. 17, 6527-6540. 10. Qu, J. et al. (2001) Mol. Cell. Biol. 21, 3523-3533. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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