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Antigenic Specificity | PTK2B |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | affinity purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody detects endogenous levels of PTK2B and does not cross-react with related proteins. UniPort Summary Function: Non-receptor protein-tyrosine kinase that regulates reorganization of the actin cytoskeleton, cell polarization, cell migration, adhesion, spreading and bone remodeling. Plays a role in the regulation of the humoral immune response, and is required for normal levels of marginal B-cells in the spleen and normal migration of splenic B-cells. Required for normal macrophage polarization and migration towards sites of inflammation. Regulates cytoskeleton rearrangement and cell spreading in T-cells, and contributes to the regulation of T-cell responses. Promotes osteoclastic bone resorption; this requires both PTK2B/PYK2 and |
Immunogen | Immunogen: Purified recombinant human PTK2B protein fragments expressed in E Coli. Cellular Localization: Cytoplasm |
Other Names | [PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK], [PTK2B; PTK2B; PKB; PTK; CAKB; FAK2; PYK2; CADTK; FADK2; RAFTK; FAK2; PYK2; RAFTK; CADTK; CAK-beta; CAKB; FADK 2; RAFTK] |
Gene, Accession # | [PTK2B], Gene ID: 2185, NCBI: NP_004094.3, UniProt: Q14289 |
Catalog # | MBS857863 |
Price | $300 |
Order / More Info | PTK2B Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |