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Antigenic Specificity | IL15RA |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: IL15RA antibody detects endogenous levels of total IL15RA. Function: High-affinity receptor for interleukin-15. Can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Expression of different isoforms may alter or interfere with signal transduction. Isoform 5, isoform 6, isoform 7 and isoform 8 do not bind IL15. Signal transduction involves SYK.Subunit Structure: The interleukin-15 receptor IL15R is a heterotrimer of IL15RA, IL2RB and IL2RG. IL15RA also self-associates (By similarity). Interacts with SYK.Post-translational Modifications: A soluble form (sIL-15RA) arises from proteolytic shedding of the membrane-anchored receptor. The cleavage involves AD |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Secreted > Extracellular Space; Membrane. Nucleus Membrane. Mainly found associated with the nuclear membrane and endoplasmic reticulum membrane. Golgi Apparatus Membrane. Cytoplasmic Vesicle Membrane. Membrane. Isoform 5, isoform 6, isoform 7 and isoform 8 are associated with endoplasmic reticulum, golgi and cytoplasmic vesicles, but not with the nuclear membrane. Tissue Specificity: Isoform 1, isoform 3, isoform 4, isoform 5, isoform 6, is |
Other Names | [AA690181; CD215; I15RA_HUMAN; IL 15R alpha; IL-15 receptor subunit alpha; IL-15R-alpha; IL-15RA; Il15ra; Interleukin 15 receptor alpha; Interleukin 15 receptor subunit alpha; MGC104179; sIL-15 receptor subunit alpha; sIL-15R-alpha; sIL-15RA; Soluble interleukin 15 receptor subunit alpha; Soluble interleukin-15 receptor subunit alpha] |
Gene, Accession # | [IL15RA], Gene ID: 3601, NCBI: NP_001230468.1, UniProt: Q13261 |
Catalog # | MBS9606161 |
Price | $240, $280 |
Order / More Info | IL15RA Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |