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Antigenic Specificity | NSUN2 - N-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | cow, dog, guinea pig, horse, human, mouse, rabbit, rat, yeast, zebrafish |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against NSUN2. It was validated on Western BlotTarget Description: NSUN2 is a RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. NSUN2 methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. It may act downstream of Myc to regulate epidermal cell growth and proliferation. And it is required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NSUN2 |
Other Names | [tRNA (cytosine(34)-C(5))-methyltransferase isoform 1; tRNA (cytosine(34)-C(5))-methyltransferase; tRNA (cytosine(34)-C(5))-methyltransferase; NOP2/Sun RNA methyltransferase family member 2; Myc-induced SUN domain-containing protein; Misu; NOL1/NOP2/Sun domain family member 2; Substrate of AIM1/Aurora kinase B; tRNA (cytosine-5-)-methyltransferase; tRNA methyltransferase 4 homolog; hTrm4] |
Gene, Accession # | [NSUN2], Gene ID: 54888, NCBI: NP_060225, UniProt: Q08J23 |
Catalog # | MBS3209179 |
Price | $335 |
Order / More Info | NSUN2 - N-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |