NSUN2 - N-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNSUN2 - N-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciescow, dog, guinea pig, horse, human, mouse, rabbit, rat, yeast, zebrafish
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against NSUN2. It was validated on Western BlotTarget Description: NSUN2 is a RNA methyltransferase that methylates tRNAs, and possibly RNA polymerase III transcripts. NSUN2 methylates cytosine to 5- methylcytosine (m5C) at positions 34 and 48 of intron-containing tRNA(Leu)(CAA) precursors, and at positions 48, 49 and 50 of tRNA(Gly)(GCC) precursors. It may act downstream of Myc to regulate epidermal cell growth and proliferation. And it is required for proper spindle assembly and chromosome segregation, independently of its methyltransferase activity.
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NSUN2
Other Names[tRNA (cytosine(34)-C(5))-methyltransferase isoform 1; tRNA (cytosine(34)-C(5))-methyltransferase; tRNA (cytosine(34)-C(5))-methyltransferase; NOP2/Sun RNA methyltransferase family member 2; Myc-induced SUN domain-containing protein; Misu; NOL1/NOP2/Sun domain family member 2; Substrate of AIM1/Aurora kinase B; tRNA (cytosine-5-)-methyltransferase; tRNA methyltransferase 4 homolog; hTrm4]
Gene, Accession #[NSUN2], Gene ID: 54888, NCBI: NP_060225, UniProt: Q08J23
Catalog #MBS3209179
Price$335
Order / More InfoNSUN2 - N-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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