Phospho-AP-1 (Ser63) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-AP-1 (Ser63)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB); ELISA (EIA); Immunohistochemistry (IHC)
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DescriptionPolyclonal antibody to detect endogenous levels of AP-1 protein when phosphorylated at Ser63 in human; mouse and rat. Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells. Binds to the USP28 promoter in colorectal cancer (CRC) cells
ImmunogenImmunogen: Synthesized peptide derived from human AP-1 around the phosphorylation site of S63 (10-90aa)
Other Names[JUN; Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39], [JUN]
Gene, Accession #[AP-1], Gene ID: 3725, NCBI: NP_002219.1, UniProt: P05412
Catalog #MBS846127
Price$335
Order / More InfoPhospho-AP-1 (Ser63) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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