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Antigenic Specificity | Phospho-AP-1 (Ser63) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB); ELISA (EIA); Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Polyclonal antibody to detect endogenous levels of AP-1 protein when phosphorylated at Ser63 in human; mouse and rat. Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells. Binds to the USP28 promoter in colorectal cancer (CRC) cells |
Immunogen | Immunogen: Synthesized peptide derived from human AP-1 around the phosphorylation site of S63 (10-90aa) |
Other Names | [JUN; Transcription factor AP-1; Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39], [JUN] |
Gene, Accession # | [AP-1], Gene ID: 3725, NCBI: NP_002219.1, UniProt: P05412 |
Catalog # | MBS846127 |
Price | $335 |
Order / More Info | Phospho-AP-1 (Ser63) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |