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Antigenic Specificity | PPP5C |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Serine/threonine-protein phosphatase that dephosphorylates a myriad of proteins involved in different signaling pathways including the kinases CSNK1E, ASK1/MAP3K5, PRKDC and RAF1, the nuclear receptors NR3C1, PPARG, ESR1 and ESR2, SMAD proteins and TAU/MAPT. Implicated in wide ranging cellular processes, including apoptosis, differentiation, DNA damage response, cell survival, regulation of ion channels or circadian rhythms, in response to steroid and thyroid hormones, calcium, fatty acids, TGF-beta as well as oxidative and genotoxic stresses. Participates in the control of DNA damage response mechanisms such as checkpoint activation and DNA damage repair through, for instance, the regulation ATM/ATR-signaling and dephosphorylation of PRKDC |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human PPP5C (NP 006238.1). |
Other Names | [PP5; PPT; PPP5] |
Gene, Accession # | [PPP5C], Gene ID: 5536, NCBI: NP_006238.1, UniProt: P53041 |
Catalog # | MBS8548582 |
Price | $280 |
Order / More Info | PPP5C Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |