DFFA (C-term), 304-331 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | DFFA (C-term), 304-331 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This DFFA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 304-331 amino acids from the C-terminal region of human DFFA. DFFA is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB ha |
| Immunogen | n/a |
| Other Names | [DNA fragmentation factor subunit alpha; DNA fragmentation factor 45 kDa subunit; DFF-45; Inhibitor of CAD; ICAD; DFFA; DFF1; DFF45] |
| Gene, Accession # | [DFFA], Gene ID: 1676, NCBI: NP_004392.1, UniProt: O00273 |
| Catalog # | MBS9211495 |
| Price | $165, $370 |
| Order / More Info | DFFA (C-term), 304-331 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Ninios,Y.P., et.al., Apoptosis 15 (2), 128-138 (2010) Banas,T., et.al., Eur. J. Obstet. Gynecol. Reprod. Biol. 146 (1), 87-91 (2009) Trynka,G., et.al., Gut 58 (8), 1078-1083 (2009) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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