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Antigenic Specificity | B Raf |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron. Frequently mutated in thyroid cancers, skin melanomas and at lower frequency in a wide range of human cancers. An activating mutation, mimicking phosphorylation of the activation loop, is seen in 60% of malignant melanoma samples. Raf mutations are generally exclusive to Ras activating mutations. |
Immunogen | Immunogen: A synthesized peptide derived from human B Raf |
Other Names | [B-RAF; p94; NS7; B-Raf proto-oncogene serine/threonine-protein kinase; BRAF; BRAF1] |
Gene, Accession # | [B Raf], Gene ID: 673, NCBI: NP_004324.2, UniProt: P15056 |
Catalog # | MBS8542396 |
Price | $280 |
Order / More Info | B Raf Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |