Edit |   |
---|---|
Antigenic Specificity | GLK, CT |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | ammonium sulfate precipitate |
Size | 0.2 mL |
Concentration | 0.68mg/ml |
Applications | ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human GLK. GLK is a member of the Ste20 family of serine/threonine protein kinases. The protein belongs to the subfamily that consists of members, such as germinal center kinase (GCK), that are characterized by an N-terminal catalytic domain and C-terminal regulatory domain. The kinase activity of the encoded protein can be stimulated by UV radiation and tumor necrosis factor-alpha. The protein specifically activates the c-Jun N-terminal kinase (JNK) signaling pathway. Evidence suggests that it functions upstream of mitogen-activated protein kinase kinase kinase 1 (MEKK1). This gene previously was referred to as RAB8-interacting protein-like 1 (RAB8IPL1), but it has been renamed mitogen-activated protein kinase kinase kinase kina |
Immunogen | Immunogen: KLH-conugated synthetic peptide mapping to a fragment of residues within amino acids 423-453 in the C-terminal region of human GLK. |
Other Names | GLK, CT (Germinal Center Kinase Related Protein Kinase, Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, MAP4K3, MAPKKKK3, MAPK/ERK Kinase Kinase Kinase 3, MEK Kinase Kinase 3, MEKKK 3, RAB8IPL1) |
Gene, Accession # | Gene ID: 1244139, NCBI: NP_245729.1, UniProt: Q8IVH8 |
Catalog # | MBS623463 |
Price | $610 |
Order / More Info | GLK, CT Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |