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Antigenic Specificity | CD163 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.05 mL, 0.1 mL, 0.2 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 750-1050 of human CD163 (NP 004235.4). Calculated MW: 121 kDa/ 124 kDa/ 125 kDa Observed MW: 180 kDa Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
Other Names | [CD163; M130; MM130; SCARI1; CD163 molecule] |
Gene, Accession # | [CD163], Gene ID: 9332, NCBI: NP_004235.4, UniProt: Q86VB7 |
Catalog # | MBS9128633 |
Price | $200, $275, $430 |
Order / More Info | CD163 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |