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Antigenic Specificity | Mouse CD49d |
Clone | [R1-2] |
Host Species | Rat |
Reactive Species | mouse |
Isotype | IgG2b |
Format | biotin conjugate |
Size | 0.1 mg, 0.3 mg |
Concentration | Antibody concentration: 0.1 mg/ml |
Applications | Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD49d (a4 chain of VLA-4; LPAM-2) (Mouse CD49d (a4 integrin)). anti-mouse CD49d monoclonal antibody reacts with a4 integrin, which helps to mediate cell-cell and cell-matrix interactions. a4 integrin combines with b1 and b7integrin to form VLA-4 and LPAM-1 (Peyers patch homing receptor) respectively. VLA-4 is expressed on most peripheral lymphocytes, thymocytes and monocytes. LPAM-1 is found on peripheral lymphocytes, but few thymocytes. Fibronectin and VCAM-1 act as ligands for both VLA-4 and LPAM-1. LPAM-1 also binds the mucosal vascular addressin MAdCAM-1. (1) Applications of this clone include flow cytometry, immunoprecipitation and immunohistochemistry. (1,2,3) |
Immunogen | Immunogen: Peyers Patch HEV binding lymphoma line (TK1). Donor: Fisher Spleen. Fusion Partner: P3x63Ag8.653 |
Other Names | n/a |
Gene, Accession # | [CD49d] |
Catalog # | MBS520174 |
Price | $210, $355 |
Order / More Info | Mouse CD49d Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |