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Antigenic Specificity | WT1 (Center E361), 346-375 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: Xenopus, mouse, porcine, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.33 |
Applications | Immunofluorescence (IF), ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This WT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the Central region of human WT1. This gene encodes a transcription factor that containsfour zinc-finger motifs at the C-terminus and aproline/glutamine-rich DNA-binding domain at the N-terminus. It hasan essential role in the normal development of the urogenitalsystem, and it is mutated in a small subset of patients with Wilm'stumors. This gene exhibits complex tissue-specific and polymorphicimprinting pattern, with biallelic, and monoallelic expression fromthe maternal and paternal alleles in different tissues. Multipletranscript variants have been described. In several variants, the |
Immunogen | n/a |
Other Names | [Wilms tumor protein; WT33; WT1] |
Gene, Accession # | [WT1], Gene ID: 7490, NCBI: NP_000369.3, UniProt: P19544 |
Catalog # | MBS9203569 |
Price | $165, $370 |
Order / More Info | WT1 (Center E361), 346-375 Antibody from MYBIOSOURCE INC. |
Product Specific References | Sitaram, R.T., et al. Br. J. Cancer 103(8):1255-1262(2010) Dohi, S., et al. Anticancer Res. 30(8):3187-3192(2010) Rocquain, J., et al. BMC Cancer 10, 401 (2010) : Wagner, K.D., et al. J. Cell. Sci. 116 (PT 9), 1653-1658 (2003) : Mitsuya, K., et al. Hum. Mol. Genet. 6(13):2243-2246(1997) |