WT1 (Center E361), 346-375 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityWT1 (Center E361), 346-375
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman (predicted reactivity: Xenopus, mouse, porcine, rat)
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.33
ApplicationsImmunofluorescence (IF), ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunohistochemistry (IHC)
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DescriptionThis WT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-375 amino acids from the Central region of human WT1. This gene encodes a transcription factor that containsfour zinc-finger motifs at the C-terminus and aproline/glutamine-rich DNA-binding domain at the N-terminus. It hasan essential role in the normal development of the urogenitalsystem, and it is mutated in a small subset of patients with Wilm'stumors. This gene exhibits complex tissue-specific and polymorphicimprinting pattern, with biallelic, and monoallelic expression fromthe maternal and paternal alleles in different tissues. Multipletranscript variants have been described. In several variants, the
Immunogenn/a
Other Names[Wilms tumor protein; WT33; WT1]
Gene, Accession #[WT1], Gene ID: 7490, NCBI: NP_000369.3, UniProt: P19544
Catalog #MBS9203569
Price$165, $370
Order / More InfoWT1 (Center E361), 346-375 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesSitaram, R.T., et al. Br. J. Cancer 103(8):1255-1262(2010) Dohi, S., et al. Anticancer Res. 30(8):3187-3192(2010) Rocquain, J., et al. BMC Cancer 10, 401 (2010) : Wagner, K.D., et al. J. Cell. Sci. 116 (PT 9), 1653-1658 (2003) : Mitsuya, K., et al. Hum. Mol. Genet. 6(13):2243-2246(1997)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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