MRN Complex Antibody Sampler Kit Antibody from MYBIOSOURCE INC.
Search, find, compare suppliers for anti-MRN Complex Antibody Sampler Kit antibody, protein, ELISA kits.
| Edit | |
|---|---|
| Antigenic Specificity | MRN Complex Antibody Sampler Kit |
| Clone | n/a |
| Host Species | n/a |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 1 kit |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Background: The Mre11-Rad50-Nbs1 (MRN) complex is a key mediator of genome maintenance, playing important roles in meiosis, telomere stability at the ends of chromosomes, and the cellular responses to DNA damage. Homodimers of the Mre11 and Rad50 subunits form a tetramer core that binds directly to DNA and associates with the Nbs1 subunit. The complex functions as a sensor of DNA damage and localizes to DNA double-strand breaks. At these DNA lesions, the MRN complex tethers DNA ends and processes free strands via the endonuclease and exonuclease activities of Mre11. In addition to stimulating both homologous recombination and nonhomologous end joining repair DNA pathways, MRN activates DNA damage checkpoint signaling cascades regulating cel |
| Immunogen | n/a |
| Other Names | n/a |
| Gene, Accession # | [MRN] |
| Catalog # | MBS2550061 |
| Price | $295 |
| Order / More Info | MRN Complex Antibody Sampler Kit Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
Return to Antibodies