mCD196 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | mCD196 |
| Clone | [ABM40H1] |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG2a kappa |
| Format | Protein G purified |
| Size | 0.025 mg, 0.1 mg |
| Concentration | n/a |
| Applications | Western Blot (WB) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD196 displays a high degree of genetic homology between mouse and human. Moreover, in both species it is chromosomally segregated from the main chemokine receptor gene cluster. mCD196 is expressed by myeloid DCs (dendritic cells), mature B cells, subpopulations of memory/effector CD4+ and CD8+ T cells, but not plasmacytoid DCs or naive T cells. mCD196 mediates their migration and function via stimulation with its ligand CCL20 (also known as macrophage inflammatory protein (MIP)-3alpha. mCD196 expression has been correlated with stage and prognosis in a variety of cancers including hepatocellular carcinoma, colorectal carcinoma, glioma, and non-small cell lung cancer. It is also believed to play a role in regulation of cancer progression. |
| Immunogen | Immunogen Information: Full length recombinant protein from mCD196 was used as the immunogen for this antibody. |
| Other Names | [C-C chemokine receptor type 6; Chemokine receptor-like 3; G-protein coupled receptor 29; LARC receptor], [CCR6] |
| Gene, Accession # | [CD196], Gene ID: 1235, NCBI: P51684.2, UniProt: P51684 |
| Catalog # | MBS668422 |
| Price | $120, $175 |
| Order / More Info | mCD196 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
Profile of MYBIOSOURCE INC.
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