MDC1 - C-terminal region Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMDC1 - C-terminal region
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesdog, guinea pig, human
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB)
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DescriptionThis is a rabbit polyclonal antibody against MDC1. It was validated on Western BlotTarget Description: The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci.
ImmunogenImmunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MDC1
Other Names[mediator of DNA damage checkpoint protein 1; Mediator of DNA damage checkpoint protein 1; mediator of DNA damage checkpoint protein 1; mediator of DNA damage checkpoint 1; Nuclear factor with BRCT domains 1]
Gene, Accession #[MDC1], Gene ID: 9656, NCBI: NP_055456, UniProt: Q14676
Catalog #MBS3203305
Price$335
Order / More InfoMDC1 - C-terminal region Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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