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Antigenic Specificity | MDC1 - C-terminal region |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | dog, guinea pig, human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This is a rabbit polyclonal antibody against MDC1. It was validated on Western BlotTarget Description: The protein encoded by this gene contains an N-terminal forkhead domain, two BRCA1 C-terminal (BRCT) motifs and a central domain with 13 repetitions of an approximately 41-amino acid sequence. The encoded protein is required to activate the intra-S phase and G2/M phase cell cycle checkpoints in response to DNA damage. This nuclear protein interacts with phosphorylated histone H2AX near sites of DNA double-strand breaks through its BRCT motifs, and facilitates recruitment of the ATM kinase and meiotic recombination 11 protein complex to DNA damage foci. |
Immunogen | Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MDC1 |
Other Names | [mediator of DNA damage checkpoint protein 1; Mediator of DNA damage checkpoint protein 1; mediator of DNA damage checkpoint protein 1; mediator of DNA damage checkpoint 1; Nuclear factor with BRCT domains 1] |
Gene, Accession # | [MDC1], Gene ID: 9656, NCBI: NP_055456, UniProt: Q14676 |
Catalog # | MBS3203305 |
Price | $335 |
Order / More Info | MDC1 - C-terminal region Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |