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Antigenic Specificity | CD82 (ST6) (C-term), 239-267 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 2 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CD82 (ST6) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-267 amino acids from the C-terminal region of human CD82 (ST6). The ST6 metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients. |
Immunogen | n/a |
Other Names | [CD82 antigen; C33 antigen; IA4; Inducible membrane protein R2; Metastasis suppressor Kangai-1; Suppressor of tumorigenicity 6 protein; Tetraspanin-27; Tspan-27; CD82; CD82; KAI1; SAR2; ST6; TSPAN27] |
Gene, Accession # | [CD82], Gene ID: 3732, NCBI: NP_001020015.1, UniProt: P27701 |
Catalog # | MBS9205333 |
Price | $165, $370 |
Order / More Info | CD82 (ST6) (C-term), 239-267 Antibody from MYBIOSOURCE INC. |
Product Specific References | Zhang, X.A., et al., J. Biol. Chem. 278(29):27319-27328 (2003). Zhang, X.A., et al., Cancer Res. 63(10):2665-2674 (2003). Yang, J., et al., Ai Zheng 22(5):533-536 (2003). Sauer, G., et al., Oncol. Rep. 10(2):405-410 (2003). Ito, Y., et al., Pathol Res Pract 199(2):79-83 (2003). |