Phospho-c-Jun- S63 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPhospho-c-Jun- S63
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.05 mL, 0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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Descriptionc-Jun is a member of the Jun Family containing c-Jun, JunB and JunD, and is a component of the transcription factor AP-1 (activator protein-1). AP-1 is composed of dimers of Fos, Jun and ATF family members and binds to and activates transcription at TRE/AP-1 elements (reviewed in 1). Extracellular signals including growth factors, chemokines and stress activate AP-1-dependent transcription. The transcriptional activity of c-Jun is regulated by phosphorylation at Ser63 and Ser73 through SAPK/JNK (reviewed in 2). Knock-out studies in mice have shown that c-Jun is essential for embryogenesis (3), and subsequent studies have demonstrated roles for c-Jun in various tissues and developmental processes including axon regeneration (4), liver regene
ImmunogenImmunogen: A phospho specific peptide corresponding to residues surrounding S63 of human c-Jun
Other Names[Phospho-Jun-S63: AP1; AP-1; c-Jun; JUN], [JUN; JUN; AP1; AP-1; c-Jun; AP1]
Gene, Accession #[Jun], Gene ID: 3725, NCBI: P05412.2, UniProt: P05412
Catalog #MBS125792
Price$235, $350, $525
Order / More InfoPhospho-c-Jun- S63 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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