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Antigenic Specificity | Human Cystatin A |
Clone | [PAT1B12AT] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 heavy chain and k light chain. |
Format | Protein A purified |
Size | 0.005 mg, 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Western Blot (WB), Flow Cytometry (FC/FACS), Immunocytochemistry (ICC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cystatin-A is the intracellular inhibitor of cysteine proteinase cathepsin B (CatB) and belongs to family 1 of the cystatin superfamily of inhibitor proteins. CSTA is a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. It has been proposed that extracellular CatB together with other classes of proteinases are all subjected to a cascade-like manner of activation. CatB and its inhibitor Cystatin-A are involved in degradation of extracellular matrix proteins during tissue remodeling. CSTA is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Cystatin-A has been reported to be found in high |
Immunogen | Immunogen: Anti-human CSTA mAb, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CSTA protein 1-98 amino acids purified from E Coli. |
Other Names | [CSTA; Cystatin-A; Cystatin-AS; Stefin-A; CSTA; STF1; STFA; Cystatin A, Mouse Human], [CSTA; CSTA; AREI; PSS4; STF1; STFA; STF1; STFA] |
Gene, Accession # | [CSTA], Gene ID: 1475, NCBI: NP_005204.1, UniProt: P01040 |
Catalog # | MBS146692 |
Price | $140, $205, $505 |
Order / More Info | Human Cystatin A Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |