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Antigenic Specificity | Phospho-Ezrin (Thr566) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Phospho-Ezrin (Thr566) antibody detects endogenous levels of Ezrin only when phosphorylated at Threonine 566. Description: The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton.Function: Probably involved in connections of major cytoskeletal structures to the plasma membrane. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with PLEKHG6, required for normal macropinocytosis.Subunit Structure: Interacts with MPP5 and SLC9A3R2. Found in a complex with EZR, PO |
Immunogen | Immunogen: A synthesized peptide derived from human Ezrin around the phosphorylation site of Threonine 566 Subcellular Location: Apical Cell Membrane. Cell Projection. Cell Projection > Microvillus Membrane. Cell Projection > Ruffle Membrane. Cytoplasm > Cell Cortex. Cytoplasm > Cytoskeleton. Localization to the apical membrane of parietal cells depends on the interaction with MPP5. Localizes to cell extensions and peripheral processes of astrocytes (By similarity). Microvillar Peripheral Membra |
Other Names | [Villin 2 ezrin; CVIL; CVL; Cytovillin 2; Cytovillin; DKFZp762H157; Epididymis secretory protein Li 105; EZR; EZRI_HUMAN; Ezrin; FLJ26216; HEL S 105; MGC1584; p81; VIL 2; VIL2; Villin 2 (ezrin); Villin 2; Villin-2; Villin2] |
Gene, Accession # | [EZR], Gene ID: 7430, NCBI: NP_001104547.1, UniProt: P15311 |
Catalog # | MBS9600943 |
Price | $240, $280 |
Order / More Info | Phospho-Ezrin (Thr566) Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |