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Antigenic Specificity | RPC4 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: RPC4 antibody detects endogenous levels of total RPC4. Function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway (By similarity).Su |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Nuclear Predicted Cross Reactivity: Pig, Bovine, Sheep, Rabbit, Dog Similarity: Pig (91%), Bovine (91%), Sheep (91%), Rabbit (82%), Dog (91%) |
Other Names | [AI326118; AW489084; BN51 (BHK21) temperature sensitivity complementing; BN51; BN51T; DNA directed RNA polymerase III 47 kDa polypeptide; DNA directed RNA polymerase III subunit D; POLR3D; Polymerase (RNA) III (DNA directed) polypeptide D; Polymerase (RNA) III (DNA directed) polypeptide D, 44kDa; Protein BN51; RNA polymerase III subunit C4; RPC4; RPC53; Temperature sensitive complementation cell cycle specific tsBN51; TSBN51] |
Gene, Accession # | [RPC4], Gene ID: 661, NCBI: NP_001713.2, UniProt: P05423 |
Catalog # | MBS9605462 |
Price | $240, $280 |
Order / More Info | RPC4 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |