alpha-Synuclein Antibody from MYBIOSOURCE INC.

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Antigenic Specificityalpha-Synuclein
Clone[Syn 211]
Host SpeciesMouse
Reactive Specieshuman.
IsotypeIgG1
FormatProtein A purified
Size0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionThis antibody recognizes the 19 kDa protein, -synuclein, which belongs to a family of small cytoplasmic proteins expressed predominantly in neurons. The epitope maps to amino acid residues 121-125 of human -synuclein. -synuclein may be involved in neuronal plasticity and could act as a molecular chaperone that mediates the transformation of soluble A into insoluble amyloid. The protein is a major component of Lewy bodies, the pathological hallmark of Parkinson?s disease, and is also observed in senile plaques of Alzheimer?s disease patients. Human -synuclein appears to be phosphorylated at two major sites, serine 129 and serine 87, and phosphorylation may play a role in the functional regulation of the protein.
ImmunogenImmunogen: Recombinant human alpha-synuclein.
Other Names[Non-A beta component of AD amyloid; Non-A4 component of amyloid precursor; NACP], [SNCA; SNCA; PD1; NACP; PARK1; PARK4; NACP; PARK1; NACP]
Gene, Accession #[alpha-Synuclein], Gene ID: 6622, NCBI: NP_000336.1, UniProt: P37840
Catalog #MBS395263
Price$615
Order / More Infoalpha-Synuclein Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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