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Antigenic Specificity | NEK9 (C-term), 846-877 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This NEK9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 846-877 amino acids from the C-terminal region of human NEK9. NEK9, a member of the NIMA subfamily of Ser/Thr protein kinases, is a pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. It phosphorylates different histones (serine and threonine residues on H3), myelin basic protein, beta-casein (serine residues), and BICD2. NEK9 is activated during mitosis by intramolecular autophosphorylation. Activity and autophosphorylation is activated by manganese >> magnesium ions, and is sensitive to increasing concentration of detergents. This protein is not cell-cycle regulated bu |
Immunogen | n/a |
Other Names | [Serine/threonine-protein kinase Nek9; Nercc1 kinase; Never in mitosis A-related kinase 9; NimA-related protein kinase 9; NimA-related kinase 8; Nek8; NEK9; KIAA1995; NEK8; NERCC] |
Gene, Accession # | [NEK9], Gene ID: 91754, NCBI: NP_149107.4, UniProt: Q8TD19 |
Catalog # | MBS9202207 |
Price | $165, $370 |
Order / More Info | NEK9 (C-term), 846-877 Antibody from MYBIOSOURCE INC. |
Product Specific References | Tan,B.C. et al. J. Biol. Chem. 279 (10), 9321-9330 (2004) Belham,C. et al. J. Biol. Chem. 278 (37), 34897-34909 (2003) Roig, J. et al. Genes Dev. 16(13):1640-1658 (2002). Holland, P.M. et al. J. Biol. Chem. 277(18):16229-16240 (2002). Strausberg, R.L. et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903 (2002). |