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Antigenic Specificity | PCSK6 (C-term), 659-688 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PCSK6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 659-688 amino acids from the C-terminal region of human PCSK6. The protein encoded by this gene belongs to thesubtilisin-like proprotein convertase family. The members of thisfamily are proprotein convertases that process latent precursorproteins into their biologically active products. This encodedprotein is a calcium-dependent serine endoprotease that can cleaveprecursor protein at their paired basic amino acid processingsites. Some of its substrates are - transforming growth factor betarelated proteins, proalbumin, and von Willebrand factor. This geneis thought to play a role in tumor progression. Altern |
Immunogen | n/a |
Other Names | [Proprotein convertase subtilisin/kexin type 6; 3421-; Paired basic amino acid cleaving enzyme 4; Subtilisin-like proprotein convertase 4; SPC4; Subtilisin/kexin-like protease PACE4; PCSK6; PACE4] |
Gene, Accession # | [PCSK6], Gene ID: 5046, NCBI: NP_002561.1, UniProt: P29122 |
Catalog # | MBS9206912 |
Price | $165, $370 |
Order / More Info | PCSK6 (C-term), 659-688 Antibody from MYBIOSOURCE INC. |
Product Specific References | Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Fuller, J.A., et al. Invest. Ophthalmol. Vis. Sci. 50(12):5759-5768(2009) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009) Blanchet, M.H., et al. EMBO J. 27(19):2580-2591(2008) |