MART-1 / Melan-A / MLANA (Melanoma Marker) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityMART-1 / Melan-A / MLANA (Melanoma Marker)
Clone[M2-9E3]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG2b, kappa
Formatunconjugated
Size0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml)
Concentrationn/a
ApplicationsFlow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin
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DescriptionThis antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
ImmunogenImmunogen: Recombinant hMART-1 protein
Other Names[Antigen LB39-AA, Antigen SK29-AA, Melanoma antigen recognized by T-cells 1, MLAN-A, MLANA], [MLANA; MLANA; MART1; MART-1; MART1; MART-1]
Gene, Accession #[MLANA], Gene ID: 2315, NCBI: NP_005502.1, UniProt: Q16655
Catalog #MBS438008
Price$190, $340, $340
Order / More InfoMART-1 / Melan-A / MLANA (Melanoma Marker) Antibody from MYBIOSOURCE INC.
Product Specific ReferencesKawakami Y, et. al. Journal of Immunological Methods, 1997, 202(1):13-25. Marincola FM, et. al. J of Immunotherapy with Emphasis on Tumor Immunol, 1996, 19(3):192-205
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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