POLR3B Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPOLR3B
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
FormatProtein G purified
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Immunohistochemistry (IHC)
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DescriptionDNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity). Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-
ImmunogenImmunogen: Recombinant Human DNA-directed RNA polymerase III subunit RPC2 protein (831-939AA)
Other Names[DNA-directed RNA polymerase III subunit RPC2; RNA polymerase III subunit C2; C128; DNA-directed RNA polymerase III 127.6 kDa polypeptide; DNA-directed RNA polymerase III subunit B; POLR3B]
Gene, Accession #[POLR3B], Gene ID: 55703, NCBI: NP_001154180.1, UniProt: Q9NW08
Catalog #MBS7106321
Price$160, $235
Order / More InfoPOLR3B Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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