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Antigenic Specificity | MART-1/Melan-A/MLANA (Melanoma Marker) |
Clone | [rMLANA/788] |
Host Species | Mouse |
Reactive Species | human, mouse, rat, dog. |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This MAb labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. |
Immunogen | Immunogen: Recombinant full-length human MART-1 protein. Cellular Localization: Cytoplasmic |
Other Names | [Antigen LB39-AA; Antigen SK29-AA; Melanoma antigen recognized by T-cells 1; MLAN-A; MLANA], [MART-1] |
Gene, Accession # | [MLANA], Gene ID: 2315, NCBI: NP_005502.1, UniProt: Q16655 |
Catalog # | MBS439962 |
Price | $190, $340, $340 |
Order / More Info | MART-1/Melan-A/MLANA (Melanoma Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Chen Y-T, et. al. Proc Natl Acad Sci, USA, 1996, 93:5915-19. |