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Antigenic Specificity | HLCS |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | 100ug/100ul |
Applications | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jun 2011] |
Immunogen | Immunogen: Recombinant protein |
Other Names | [Hlcs; Biotin--protein ligase; biotin--protein ligase; biotin apo-protein ligase; biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase; holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase); Biotin apo-protein ligaseIncluding the following 4 domains:Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC:6.3.4.9)Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC:6.3.4.10)Alternative name(s):Holocarboxylase synthetase; HCS], [Hlcs; Hlcs; D16Jhu34; 410I21.SP6] |
Gene, Accession # | [HLCS], Gene ID: 110948, NCBI: BAB68213.1 |
Catalog # | MBS416542 |
Price | $230 |
Order / More Info | HLCS Antibody from MYBIOSOURCE INC. |
Product Specific References | (1) Bailey,L.M., Wallace,J.C. and Polyak,S.W.,et al. Holocarboxylase synthetase: correlation of protein localisation with biological function. Arch. Biochem. Biophys. 496 (1), 45-52 (2010) |