HLCS Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHLCS
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentration100ug/100ul
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionThis gene encodes an enzyme that catalyzes the binding of biotin to carboxylases and histones. The protein plays an important role in gluconeogenesis, fatty acid synthesis and branched chain amino acid catabolism. Defects in this gene are the cause of holocarboxylase synthetase deficiency. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jun 2011]
ImmunogenImmunogen: Recombinant protein
Other Names[Hlcs; Biotin--protein ligase; biotin--protein ligase; biotin apo-protein ligase; biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase; holocarboxylase synthetase (biotin- [propriony-Coenzyme A-carboxylase (ATP-hydrolysing)] ligase); Biotin apo-protein ligaseIncluding the following 4 domains:Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC:6.3.4.9)Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC:6.3.4.10)Alternative name(s):Holocarboxylase synthetase; HCS], [Hlcs; Hlcs; D16Jhu34; 410I21.SP6]
Gene, Accession #[HLCS], Gene ID: 110948, NCBI: BAB68213.1
Catalog #MBS416542
Price$230
Order / More InfoHLCS Antibody from MYBIOSOURCE INC.
Product Specific References(1) Bailey,L.M., Wallace,J.C. and Polyak,S.W.,et al. Holocarboxylase synthetase: correlation of protein localisation with biological function. Arch. Biochem. Biophys. 496 (1), 45-52 (2010)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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