REPS2 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | REPS2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: REPS2 antibody detects endogenous levels of total REPS2. Function: Involved in growth factor signaling through its influence on the Ral signaling pathway.Subunit Structure: Interacts with ASAP1 and this complex can bind paxillin. May form a ternary complex with RALBP1 and ASAP1 (By similarity). Interacts with RALBP1 and GRB2. Binding to RALBP1 does not affect the Ral-binding activity of the latter. It can form a ternary complex with activated Ral and RALBP1. Binds EPN1.Post-translational Modifications: EGF stimulates phosphorylation on Tyr-residues and induces complex formation with EGF receptor through an adapter protein such as GRB2. |
| Immunogen | Immunogen: A synthesized peptide derived from human REPS2 Tissue Specificity: Expressed at high levels in the cerebrum, cerebellum, lung, kidney, and testis. Weakly expressed in the kidney. Relatively highly expressed in androgen-dependent as compared to androgen-independent prostate cancer cell lines and xenografts. Isoform 2 is down-regulated during progression of prostate cancer. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Bovine (88%), Horse (89 |
| Other Names | [OTTHUMP00000022995; Partner of Ral binding protein 1; Partner of RalBP1; POB1; RALBP1 associated Eps domain containing 2; RALBP1 interacting protein 2; RALBP1-associated Eps domain-containing protein 2; REPS 2] |
| Gene, Accession # | [REPS2], Gene ID: 9185, NCBI: NP_001074444.1, UniProt: Q8NFH8 |
| Catalog # | MBS9610117 |
| Price | $240, $280 |
| Order / More Info | REPS2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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