DPP4 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | DPP4 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: DPP4 antibody detects endogenous levels of DPP4. Function: Cell surface glycoprotein receptor involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. Its binding to CAV1 and CARD11 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Its interaction with ADA also regulates lymphocyte-epithelial cell adhesion. In association with FAP is involved in the pericellular proteolysis of the extracellular matrix (ECM), the migration and invasion of endothelial cells into the ECM. May be involved in the promotion of lymphatic endothelial cells adhes |
| Immunogen | Immunogen: A synthesized peptide derived from human DPP4. Subcellular Location: Cell Membrane. Apical Cell Membrane. Cell Projection > Invadopodium Membrane. Cell Projection > Lamellipodium Membrane. Cell Junction. Membrane Raft. Translocated to the apical membrane through the concerted action of N-and O-Glycans and its association with lipid microdomains containing cholesterol and sphingolipids. Redistributed to membrane rafts in T-cell in a interleukin-12-dependent activation. Its interaction |
| Other Names | [CD26 antigen; ADA-binding protein; ADABP; ADCP 2; ADCP-2; ADCP2; Adenosine deaminase complexing protein 2; CD 26; CD26; CD26 antigen 3; Dipeptidyl peptidase 4; Dipeptidyl peptidase 4 soluble form; Dipeptidyl peptidase IV; Dipeptidyl peptidase IV membrane form; Dipeptidyl peptidase IV soluble form; Dipeptidyl peptidase, intestinal; Dipeptidylpeptidase 4; Dipeptidylpeptidase IV (CD26, adenosine deaminase complexing protein 2); Dipeptidylpeptidase IV; DPP 4; DPP IV; DPP IV estoenzyme; DPP4; DPP4_HUMAN; DPPIV; Intestinal dipeptidyl peptidase; T cell activation antigen CD26; T-cell activation antigen CD26; TP 103; TP103] |
| Gene, Accession # | [DPP4], Gene ID: 1803, NCBI: NP_001926.2, UniProt: P27487 |
| Catalog # | MBS9603615 |
| Price | $240, $280 |
| Order / More Info | DPP4 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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